Martin K Oehler Selected Research

Cyclin-Dependent Kinases (cdk Proteins)

12/2020

A first-in-class CDK4 inhibitor demonstrates in vitro, ex-vivo and in vivo efficacy against ovarian cancer.

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Martin K Oehler Research Topics

Disease

52	Neoplasms (Cancer) 03/2024 - 04/2002
51	Ovarian Neoplasms (Ovarian Cancer) 02/2024 - 05/2002
12	Endometrial Neoplasms (Endometrial Cancer) 09/2023 - 04/2002
10	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2011
8	Ovarian Epithelial Carcinoma 12/2022 - 07/2005
7	Carcinoma (Carcinomatosis) 11/2020 - 03/2003
4	Carcinogenesis 04/2021 - 08/2011
3	Lymphatic Metastasis 04/2021 - 01/2016
2	Ovarian Diseases (Ovarian Disease) 03/2024 - 01/2021
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2023 - 01/2019
2	Sarcoma (Soft Tissue Sarcoma) 08/2023 - 01/2015
2	Adenocarcinoma 08/2021 - 01/2021
2	Endometrial Hyperplasia 01/2021 - 04/2002
2	Uterine Cervical Dysplasia 01/2019 - 10/2017
2	Breast Neoplasms (Breast Cancer) 12/2018 - 04/2002
2	Hemorrhage 05/2017 - 09/2003
1	Hypoalbuminemia 05/2023
1	Sarcopenia 05/2023
1	Weight Loss (Weight Reduction) 01/2021
1	Retinoblastoma (Glioblastoma, Retinal) 12/2020
1	Melanoma (Melanoma, Malignant) 09/2020
1	Lung Neoplasms (Lung Cancer) 09/2020
1	Glioblastoma (Glioblastoma Multiforme) 11/2019

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 10/2023 - 01/2011
11	Biomarkers (Surrogate Marker)IBA 02/2024 - 07/2005
7	Formaldehyde (Formol)FDA Link 04/2021 - 08/2012
7	Annexin A2 (Annexin II)IBA 01/2021 - 08/2011
6	Hyaluronic Acid (Hyaluronan)IBA 10/2023 - 01/2011
6	Carboplatin (JM8)FDA LinkGeneric 12/2022 - 10/2013
6	ParaffinIBA 04/2021 - 08/2012
6	Polysaccharides (Glycans)IBA 04/2021 - 01/2016
5	Peptides (Polypeptides)IBA 11/2016 - 01/2011
4	Messenger RNA (mRNA)IBA 01/2021 - 05/2016
3	AntigensIBA 01/2023 - 01/2011
3	Adenosine Triphosphate (ATP)IBA 01/2023 - 10/2013
3	EnzymesIBA 06/2021 - 04/2013
3	Carrier Proteins (Binding Protein)IBA 01/2021 - 08/2011
3	Fibrinolysin FDA Link 01/2019 - 08/2011
2	binimetinibIBA 10/2023 - 11/2020
2	PlatinumIBA 12/2022 - 10/2013
2	ProteomeIBA 06/2022 - 01/2020
2	Levonorgestrel (Plan B)FDA LinkGeneric 08/2021 - 01/2021
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2021 - 05/2016
2	CalciumIBA 01/2021 - 05/2016
2	AcidsIBA 01/2021 - 01/2019
2	sphingosine kinaseIBA 01/2021 - 01/2017
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021 - 10/2013
2	Monoclonal AntibodiesIBA 01/2021 - 03/2017
2	Small Interfering RNA (siRNA)IBA 12/2020 - 08/2013
2	Piwi-Interacting RNAIBA 12/2020 - 01/2014
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2020 - 11/2020
2	Bevacizumab (Avastin)FDA Link 09/2020 - 01/2015
2	S100 calcium binding protein A10IBA 01/2019 - 05/2016
2	Tamoxifen FDA LinkGeneric 12/2018 - 04/2002
2	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 01/2014
2	Conditioned Culture MediaIBA 10/2013 - 08/2011
2	betaIG-H3 protein (keratoepithelin)IBA 01/2012 - 04/2011
2	Versicans (Versican)IBA 02/2011 - 01/2011
1	Matrix Metalloproteinases (MMPs)IBA 03/2024
1	Aquaporins (Water Channels)IBA 09/2023
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 04/2023
1	GelsolinIBA 04/2023
1	ThioredoxinsIBA 04/2023
1	4- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA 04/2023
1	Purinergic P2X ReceptorsIBA 01/2023
1	CationsIBA 01/2023
1	MicroRNAs (MicroRNA)IBA 12/2022
1	InterferonsIBA 06/2022
1	CytokinesIBA 06/2022
1	Amino Acids FDA Link 06/2022
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 05/2022
1	ChemokinesIBA 06/2021
1	LigandsIBA 06/2021
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 06/2021
1	Man(3)GlcNAc(2)IBA 04/2021
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2021
1	Sitagliptin Phosphate (Januvia)FDA Link 01/2021
1	SphingolipidsIBA 01/2021
1	apabetaloneIBA 01/2021
1	Metformin (Glucophage)FDA LinkGeneric 01/2021
1	ATP Binding Cassette Transporter 1IBA 01/2021
1	LH Receptors (LH Receptor)IBA 12/2020
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 12/2020
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2020
1	Cyclin D1IBA 12/2020
1	Everolimus FDA Link 12/2020
1	Cyclin DIBA 12/2020
1	gamma Catenin (Plakoglobin)IBA 01/2020
1	Drug CombinationsIBA 11/2019

Therapy/Procedure

16	Therapeutics 12/2020 - 12/2003
15	Drug Therapy (Chemotherapy) 10/2023 - 05/2002
4	Immunotherapy 01/2023 - 02/2014
4	Hysterectomy 01/2017 - 12/2004
3	Radiotherapy 08/2023 - 03/2005
3	Lasers (Laser) 11/2019 - 10/2017
2	Pelvic Exenteration 05/2023 - 10/2022
2	Intrauterine Devices (Intrauterine Device) 08/2021 - 01/2021
2	Lymph Node Excision (Lymph Node Dissection) 01/2015 - 01/2014
1	Operative Time 05/2023
1	Cytoreduction Surgical Procedures 05/2022